Essential Biochemistry - Hemoglobin Metabolism (Section 3 - No. 4)

The oxidation of protoporphyrin-IX to protoporphyrin-IX di-oxide is catalyzed by:

Heme oxygenase

Heme synthase

Uroporphyrinogen decarboxylase

Aminolevulinate dehydratase

The oxidation of protoporphyrin-IX to protoporphyrin-IX di-oxide is catalyzed by heme oxygenase